Many had welcomed genome-editing as the most exciting discovery in 21st century biology for its impressive applications. Yet, since the beginning, the lack of accuracy of the DNA-editing enzyme made it impossible to use it effectively. CIBIO, the Centre for Integrative Biology of the University of Trento, has found a way to turn it into a precision tool that only targets a specific site of DNA that needs to be removed. In this way it will be possible to use genome-editing to correct sequences of genes, for example in patients with genetic disorders or cancer. The study, conducted in Trento, has been published in “Nature Biotechnology”
