A research team of the University of Trento used genome editing to permanently correct two of the mutations that cause the disease. Instead of animal models, organoids derived from patients' cells were used in this study. The research work was carried out in collaboration with KU Leuven, in Belgium, with support from the Italian foundation for research on cystic fibrosis and the participation of the Cystic fibrosis association of Trentino. The results were published today in "Nature Communications"